Health & Fitness, Weight Loss Gamma Hydroxybutyrate (GHB) is a central nervous system depressant that is commonly used as a recreational drug. It is known for its sedative and euphoric effects, making it a popular choice among individuals looking to enhance their social experiences or relax after a long day. While GHB is a controlled substance in many countries due to its potential for abuse and addiction, it is still widely available for purchase online.